Here is an example design for a charity's three-fold leaflet. The front cover uses a strong photo that has been cropped to fit the dimensions of the leaflet; the topic of the leaflet and the charity's logo are at the bottom of the front page.
The back page features the contact details of the charity, while the first page that is visible after opening the leaflet features a case study with a photo.
The inside of the leaflet includes headers, text and photos that have been aligned to the left hand margin. The right-hand side of the leaflet includes a reply form.
The reply form allows people to fulfil whatever 'call to action' you are making in the leaflet, whether that is making a donation, offering to volunteer or asking for more information about the charity.